Description
NFATc1 Antibody | 36-347 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: Recombinant N-terminal human NFATc1 fragment fused to a GST-tag.
Research Area: Cancer, Immunology, Innate Immunity, Stem Cell, Functional Assays
Tested Application: FUNC, ICC, IHC, IP, WB
Application: Functional Application: Induces apoptosis with or without cross-linking (Protein A) , depending on cell type. Note: Optimal conditions must be determined.
Specificiy: Recognizes all known human NFATc1 isoforms.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Antigen affinity purified.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Liquid. In PBS containing 1mg/ml BSA and 0.02% sodium azide.
Concentration: 500 ug/ml
Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C.
Alternate Name: Nuclear Factor of Activated T Cells; Cytoplasmic 1; NFAT Transcription Complex Cytosolic Component; NF-ATc1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: NFATc1 plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 or IL-4 gene transcription. It controls gene expression in embryonic cardiac cells. Regulates not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.