NFkB-p65 (phospho-S468) polyclonal Antibody | BS4136

NFkB-p65 (phospho-S468) polyclonal Antibody | BS4136 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC IP

Application Range: IHC: 1:50~1:200 IP: 1:50~1:200

Background: p65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory prd in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibittransforming activity.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: p-NFκB-p65 (S468) polyclonal Antibody detects endogenous levels of NFκB-p65 protein when phosphorylated at Ser468.

Molecular Weight: ~ 60, 75 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: p65; p65 NF kappaB; p65 NFkB; RELA; NFKB P65; Transcription Factor p65; Nuclear factor NF-kappa-B p65 subunit; NFkB-p65; NFKB3

Immunogen: Synthetic phosphopeptide derived from human NFkB-p65 around the phosphorylation site of Serine 468.

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: NF-kB Signaling,NF-kB Signaling,Immune Cell Signaling,Signaling Pathways Activating p38 MAP KinaseSTING Signaling,T cell receptor signaling,Inhibition of Apoptosis,Contribution of Soluble Factors to EMT,