NFKBID Polyclonal Antibody | E-AB-10087

NFKBID Polyclonal Antibody | E-AB-10087 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: I-kappa-B-delta, IkappaBdelta, IkappaBNS, IkB-delta, IKBD, IKBNS, NF-kappa-B inhibitor delta, NFKBID, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor delta, T-cell activation NFKB-like protein, TA-NFKBH

Application: WB, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Background: May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human NFKBID

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 33 kDa

Molecular Weight(Observed): N/A