NGB polyclonal Antibody | BS8248

NGB polyclonal Antibody | BS8248 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: Globins are a superfamily of gas-binding heme proteins that are present in bacteria, protists, fungi, plants and animals. Globins play evolutionarily divergent roles which include binding, transport, scavenging, detoxification, and sensing of oxygen, nitric oxide and carbon monoxide. Neuroglobin (Ngb) is a hexacoordinate hemoglobin that is predominantly expressed in the vertebrate brain and may enhance oxygen supply to neural components. Neuroglobin displays a high affinity for oxygen and its presence in cerebral neurons suggests a role in neuronal responses to hypoxia or ischemia. For example, in vitro neuronal hypoxia causes an elevation in the levels of neuroglobin, which enhances neuronal cell survival. The human neuroglobin gene maps to chromosome 14q24 and encodes a 151 amino acid protein.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NGB polyclonal Antibody detects endogenous levels of NGB protein.

Molecular Weight: ~ 17 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Neuroglobin; NGB

Immunogen: Recombinant full length Human NGB.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: