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NGFRAP1 polyclonal Antibody | BS8819
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- BW-BS8819
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Description
NGFRAP1 polyclonal Antibody | BS8819 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IF
Application Range: WB: 1:500~1:2000 IF: 1:50~1:200
Background: Bex3, also known as p75NTR-associated cell death executor (NADE), nerve growth factor receptor-associated protein 1 or ovarian granulosa cell 13 kDa protein HGR74, is a member of the Bex family involved in zinc-triggered neuronal cell death. It can be found in prostate, testis, liver, ovarian granulosa cells and seminal vesicle tissue shuttling between the cytoplasm and the nucleus. Bex3 interacts with Smac (second mitochondria-derived activator of caspase) via its C-terminal and regulates apoptosis by the inhibition of Smac ubiquitination. Bex3 also interacts with itself and the NGFR p75 DEATH domain. Bex3 may play a significant role in the pathogenosis of neurogenetic diseases.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NGFRAP1 polyclonal Antibody detects endogenous levels of NGFRAP1 protein.
Molecular Weight: ~ 24 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Protein BEX3; Brain-expressed X-linked protein 3; Nerve growth factor receptor-associated protein 1; Ovarian granulosa cell 13.0 kDa protein HGR74; p75NTR-associated cell death executor; NGFRAP1; BEX3, DXS6984E, NADE
Immunogen: Recombinant full length Human NGFRAP1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: