β-Nicotinamide mononucleotide | 2733

Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation

2733 | β-Nicotinamide mononucleotide DataSheet

Alternate Name/Synonyms: β-NMN, β-Nicotinamide ribose monophosphate, NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate

Appearance: White lyophilzed solid

Formulation: N/A

CAS Number: 1094-61-7

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₁₅N₂O₈P

Molecular Weight: 334.22

Cell-Permeable?: No

Purity: ≥98% by HPLC

Solubilities: H₂O (50 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: Enhancer of hepatic insulin sensitivity

MDL Number: MFCD00038748

PubChem CID: 14180

SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)[O-])O)O)C(=O)N

InChi: InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1

InChi Key: DAYLJWODMCOQEW-TURQNECASA-N