Additional Information
Short Description: |
BCR-ABL kinase inhibitor |
Research Area: |
Cell Signaling, Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
Alternative Name(s): |
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
641571-10-0 |
Molecular Formula: |
C28H22F3N7O |
Molecular Weight: |
529,5 |
Source: |
Synthetic |
Purity: |
≥99% |
Solubility: |
Soluble in DMSO (50 mg/ml), chloroform, DMF (~3 mg/ml), water(very poorly soluble, maximum solubility in plain water is estimated to be about 10-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility), and ethanol(v |
Appearance: |
Crystalline powder |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
C5=C([N]1C=C(N=C1)C)C=C(NC(=O)C2=CC(=C(C=C2)C)NC3=NC(=CC=N3)C4=CN=CC=C4)C=C5C(F)(F)F |
InChI: |
InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37) |
InChIKey: |
HHZIURLSWUIHRB-UHFFFAOYSA-N |
Field of Use: |
For in vitro research use only. |
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