NK1.1 Antibody [PK136] (Biotin) | 98-953

NK1.1 Antibody [PK136] (Biotin) | 98-953 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Mouse

Homology: N/A

Immunogen: CE mouse spleen enriched for NK-1+ cells and bone marrow cells

Research Area: Innate Immunity

Tested Application: Flow

Application: NK1.1 Antibody [PK136] for use in flow cytometry, immunohistochemistry, and immunoprecipitation assays.

Specificiy: NK1.1

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [PK136]

Isotype: IgG2a

Conjugate: Biotin

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: Ly-55, CD161b/CD161c

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL/6, NZB, and CE) . NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.