NKIRAS1 polyclonal Antibody | BS65546

NKIRAS1 polyclonal Antibody | BS65546 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,

Application: WB,

Application Range: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: Small guanosine triphosphatases, typified by the mammalian Ras proteins, play major roles in the regulation of numerous cellular pathways. IκBinteracting Ras-like proteins, κB-Ras1 and κB-Ras2, belong to a subclass of evolutionarily conserved Ras-like proteins that differ from other Ras proteins in containing amino acids at positions 12 and 61 that are similar to those present in the oncogenic forms of Ras. These Ras-like proteins, κB-Ras1 and κB-Ras2, interact with the PEST domains of IκBa and IκBb and decrease their rate of degradation. κB-Ras2 shows 71% identity to κB-Ras1. In cells,κB-Ras proteins are associated only with NFκB:IκBb complexes and therefore may provide an explanation for the slower rate of degradation of IκBb compared with IκBa.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NKIRAS1 polyclonal Antibody detects endogenous levels of NKIRAS1 protein.

Molecular Weight: ~22kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 2400004O09Rik; I kappa B interacting Ras like protein 1; I-kappa-B-interacting Ras-like protein 1; Kappa B Ras 1; Kappa B Ras protein 1; Kappa B-Ras protein 1; KappaB Ras1; KappaB-Ras1; KBRAS 1; KBRAS1; KBRS1_HUMAN; NF kappa B inhibitor interacting Ras like protein 1; NF-kappa-B inhibitor-interacting Ras-like protein 1; NFKB inhibitor interacting Ras like 1; NFKB inhibitor interacting Ras like protein 1; NKIRAS 1; nkiras1.

Immunogen: KLH conjugated synthetic peptide derived from human NKIRAS1:131-192/192

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: