NKp46 polyclonal Antibody | BS8525

NKp46 polyclonal Antibody | BS8525 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB 1:500 - 1:2000

Background: NKp46 (lymphocyte antigen 94, LY94) is a natural cytotoxicity receptor that belongs to the immunoglobulin superfamily and is expressed by all resting or activated NK cells, but not on T cells or B cells. The NKp46 cDNA encodes a 304 amino acid type I transmembrane protein with an extracellular region preceded by a 21 residue signal peptide and two cysteine-bridged C2-type Ig-like domains. A stem connects the extracellular domain to a 19 amino acid, arginine containing-transmembrane domain. NKp46 is involved in natural cytotoxicity and is involved in the recognition and lysis of both human and murine tumor cells.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NKp46 polyclonal Antibody detects endogenous levels of NKp46 protein.

Molecular Weight: ~ 34kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD335; NCR1; LY94

Immunogen: Recombinant full length Human NKp46.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: