NKX6-2 Antibody (N-term) [APR31652G]

NKX6-2 Antibody (N-term) [APR31652G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This NKX6-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human NKX6-2.

Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:D3Z4R4}.

Molecular Weight: 29263

Clone: Polyclonal

Gene Name: NKX6-2

Gene ID: 84504

Function: Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'- (A/T) TTAATGA- 3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.

Summary: Tissue Location: Highest expression in brain.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Homeobox protein Nkx-62, Homeobox protein NK-6 homolog B, NKX6-2, GTX, NKX6B