NLGN3 polyclonal Antibody | BS60735

NLGN3 polyclonal Antibody | BS60735 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB: 1:500~1:1000

Background: Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain . Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3 . Neuroligins are expressed in excitatory neuronal synaptic clefts . Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins . Neuroexin 1∫ binds to the EF-hand domain of Neuroligin 1 and requires calcium ion . Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NLGN3 polyclonal Antibody detects endogenous levels of NLGN3 protein.

Molecular Weight: ~ 94 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Neuroligin-3; Gliotactin homolog; NLGN3; KIAA1480; NL3

Immunogen: A synthetic peptide corresponding to residues in Human NLGN3

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: