NMNAT1, human recombinant | 7561

This is the nuclear NMNAT isoform. It catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. It interacts with PARP-1/ARTD1. It protects against axonal degeneration following mechanical or toxic insults. It is widely expressed.

7561 | NMNAT1 human recombinant DataSheet

Biomolecule/Target: NMNAT1

Synonyms: Nicotinamide Mononucleotide Adenylyl-transferase 1, NMN Adenylyltransferase 1; NaMN Adenylyltransferase 1; EC 2.7.7.1.

Alternates names: Protein G

Taglines: Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP.

NCBI Gene ID #: N/A

NCBI Gene Symbol: N/A

Gene Source: N/A

Accession #: N/A

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: One unit is defined as the amount of enzyme that synthesizes 1 µmol of NAD+ per min.

Molecular Weight: 26.1 kDa

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml in 50 mM sodium phosphate, pH 8.0 containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol.

Reconstitution Instructions: Reconstitution in HO to a concentration of 5 mg/ml gives a clear solution.

Amino acid sequence: N/A