Norquetiapine dihydrochloride | 2362

A pharmacologically active metabolite of quetiapine. Activates ERK1/2 and induces release of BDNF in C6 glioma cells which may contribute to the antidepressant properties of quetiapine.

Norquetiapine is a pharmacologically active metabolite of quetiapine. Activates ERK1/2 and induces release of BDNF in C6 glioma cells which may contribute to the antidepressant properties of quetiapine.

2362 | Norquetiapine dihydrochloride DataSheet

Alternate Name/Synonyms: 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine, dihydrochloride

Appearance: Off-white solid

Formulation: N/A

CAS Number: 111974-74-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₇N₃S. 2HCl

Molecular Weight: 368.32

Cell-Permeable?: Yes

Purity: ≥98% TLC

Solubilities: DMSO

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A pharmacologically active metabolite of quetiapine.

MDL Number: N/A

PubChem CID: 19842188

SMILES: C1CN(CCN1)C2=NC3=CC=CC=C3SC4=CC=CC=C42.Cl.Cl

InChi: InChI=1S/C17H17N3S.2ClH/c1-3-7-15-13(5-1)17(20-11-9-18-10-12-20)19-14-6-2-4-8-16(14)21-15;;/h1-8,18H,9-12H2;2*1H

InChi Key: PZQCQHZDUIIKFU-UHFFFAOYSA-N