Notch3 Antibody [HMN3-133] (APC) | 77-002

Notch3 Antibody [HMN3-133] (APC) | 77-002 | Gentaur UK, US & Europe Distribution

Host: Hamster

Reactivity: Mouse

Homology: N/A

Immunogen: N/A

Research Area: Stem Cell

Tested Application: Flow

Application: N/A

Specificiy: The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clonality: Monoclonal

Clone: HMN3-133

Isotype: Armenian Hamster IgG

Conjugate: APC

Physical State: liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Concentration: batch dependent

Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.

Alternate Name: N3, hpbk, AW229011, Notch3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.