NPHS2 Polyclonal Antibody | E-AB-16657

NPHS2 Polyclonal Antibody | E-AB-16657 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Nephrosis 2, idiopathic, steroid resistant (podocin), nephrosis 2, idiopathic, steroid resistant, NPHS2, NPHS2 gene, PDCN, PODO, Podocin, SRN1

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell biology, Signal transduction, Tags and Cell markers

Background: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.

Concentration: 1.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human NPHS2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A