NPM1 Polyclonal Antibody | E-AB-40477

NPM1 Polyclonal Antibody | E-AB-40477 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: B23, MGC104254, NO38, NPM, NPM, NPM1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Nucleophosmin (nucleolar phosphoprotein B23 numatrin), Nucleophosmin, nucleophosmin nucleoplasmin family member 1, Nucleophosmin/nucleoplasmin family member 1, Numatrin

Application: WB, IHC

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: Nucleophosmin (NPM1, B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.

Concentration: 1mg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: Recombinant Mouse Nucleophosmin protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification Method: Antigen Affinity Purification

Dilution: WB 1:10000-1:20000 IHC 1:200-1:500

Clone: N/A

Conjugation: N/A

Molecular Weight(Calculated): 32 kDa

Molecular Weight(Observed): 37 kDa