NRF1 Antibody| F43927-0.08ML/F43927-0.4ML/R31050

NRF1 Antibody| F43927-0.08ML/F43927-0.4ML/R31050 | Gentaur UK, US & Europe Distribution

Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Zebrafish

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the NRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This NRF1 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 226-255 from the human protein was used as the immunogen for this NRF1 antibody.

Storage: Aliquot the NRF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A