Nrf3 (D530) polyclonal Antibody | BS9275

Nrf3 (D530) polyclonal Antibody | BS9275 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Nrf3 (nuclear factor (erythroid-derived 2) -like 3, NFE2L3, NF-E2-related factor 3, NRF3) is a transcription factor that influences placental gene expression and development. Nrf3 contains a Cap'n'collar (CNC) -type basic leucine zipper (bZIP) domain, and belongs to the CNC gene family. CNC genes play important roles in development, differentiation, oncogenesis, and stress signaling. Nrf3 protein is detectable in primary placental cytotrophoblasts. The human choriocarcinoma cell lines BeWo and JAR from trophoblastic tumors of the placenta express Nrf3 transcripts. Nrf3/MAFG heterodimers recognize nuclear factor-erythroid 2/Maf recognition element-type DNA-binding motifs. Keratinocyte growth factor (KGF) -regulates Nrf3-dependent gene expression during cutaneous wound repair.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Nrf3 (D530) polyclonal Antibody detects endogenous levels of Nrf3 protein.

Molecular Weight: ~ 76 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor, erythroid derived 2, like 3; NFE2L3; NRF3

Immunogen: Synthetic peptide, corresponding to amino acids 500-520 of Human Nrf3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: