NRG1 Polyclonal Antibody | E-AB-13305

NRG1 Polyclonal Antibody | E-AB-13305 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Acetylcholine receptor-inducing activity, Acetylcholine receptor-inducing activity, CHICK, homolog of, ARIA, Breast cancer cell differentiation factor p45, GGF, GGF2, Glial growth factor, Heregulin, heregulin, alpha (45kD, ERBB2 p185-activator), HGL, HRG, HRG1, HRGA, MST131, NDF, Neu differentiation factor, Neuregulin 1, neuregulin 1 type IV beta 1a, neuregulin 1 type IV beta 3, Neuregulin-1, NRG 1, nrg1, NRG1-IT2, NRG1, OTTHUMP00000225398, OTTHUMP00000225419, OTTHUMP00000225420, OTTHUMP00000225421, OTTHUMP00000225422, OTTHUMP00000225477, OTTHUMP00000225545, OTTHUMP00000230603, OTTHUMP00000230605, pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, ProNRG1, Sensory and motor neuron-derived factor, SMDF

Application: WB, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience, Signal Transduction

Background: The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).

Concentration: 0.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human NRG1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 70 kDa

Molecular Weight(Observed): N/A