NRG4, Human Recombinant | P1580

NRG4 belongs to the neuregulin family and contains 1 EGF-like domain. The protein is low affinity ligand for the ERBB4 tyrosine kinase receptor. It concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligandstimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG4 does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Recombinant human NRG4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

P1580 | NRG4, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, Neuregulin-4, NRG-4

Alternates names: Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, Neuregulin-4, NRG-4

Taglines: Low affinity ligand for the ERBB4 tyrosine kinase receptor.

NCBI Gene ID #: 145957

NCBI Gene Symbol: NRG4

Gene Source: Human

Accession #: Q8WWG1

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGE: >90%

Assay: SDS - PAGE

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 9.1 kDa (84aa) (N-terminal His-Tag)

Concentration:

Appearance: Liquid

Physical form description: In 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.15 M NaCl, 1 mM DTT

Reconstitution Instructions:

Amino acid sequence: aa 1-61

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans