Description
NSC 210902 inhibits casein kinase 2 (CK2) with an IC₅₀ value of 1 μM. It competitively inhibits binding of ATP with a Ki value of 0.28 µM. It minimally inhibits protein kinases JNK3, GSK3, Cdk5, MSK1 and displays selectivity for CK2.
NSC 210902 inhibits casein kinase 2 (CK2) with an IC₅₀ value of 1 μM. It competitively inhibits binding of ATP with a Ki value of 0.28 µM. It minimally inhibits protein kinases JNK3, GSK3, Cdk5, MSK1 and displays selectivity for CK2.
Alternate Name/Synonyms: 4-oxo-1,4-dihydrobenzo[h]quinoline-3-carboxylic acid; 4-hydroxybenzo[h]quinoline-3-carboxylic acid; 4-oxo-1H-benzo[h]quinoline-3-carboxylic acid; 1,4-dihydro-4-oxo-benzo[h]quinoline-3-carboxylic acid
Appearance: A crystalline solid
Formulation:
CAS Number: 51726-83-1
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₁₄H₉NO₃
Molecular Weight: 239.23
Cell-Permeable?: True
Purity: >95%
Solubilities: ~0.1 mg/ml in DMF and DMSO in 0
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A casein kinase (CK2) inhibitor
MDL Number: MFCD01829197
PubChem CID: 308815
SMILES: C1=CC=C2C(=C1)C=CC3=C2NC=C(C3=O)C(=O)O
InChi: InChI=1S/C14H9NO3/c16-13-10-6-5-8-3-1-2-4-9(8)12(10)15-7-11(13)14(17)18/h1-7H,(H,15,16)(H,17,18)
InChi Key:
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
RT |
Shelf Life: |
36 months |