NSC-348884 | B1204

NSC-348884 is a nucleophosmin inhibitor that disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC₅₀ of 1.4-4.0 μM in distinct cancer cell lines.

NSC-348884 is a nucleophosmin inhibitor that disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC₅₀ of 1.4-4.0 μM in distinct cancer cell lines.

B1204 | NSC-348884 DataSheet

Alternate Name/Synonyms: N1,N1,​N2,​N2-​tetrakis[(6-​methyl-​1H-​benzimidazol-2-​yl)​methyl]-1,​2-ethanediamine

Appearance: White Solid

Formulation: N/A

CAS Number: 81624-55-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₈H₄₀N₁₀

Molecular Weight: 636.8

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A nucleophosmin inhibitor

MDL Number: N/A

PubChem CID: 335974

SMILES: CC1=CC2=C(C=C1)N=C(N2)CN(CCN(CC3=NC4=C(N3)C=C(C=C4)C)CC5=NC6=C(N5)C=C(C=C6)C)CC7=NC8=C(N7)C=C(C=C8)C

InChi: InChI=1S/C38H40N10/c1-23-5-9-27-31(15-23)43-35(39-27)19-47(20-36-40-28-10-6-24(2)16-32(28)44-36)13-14-48(21-37-41-29-11-7-25(3)17-33(29)45-37)22-38-42-30-12-8-26(4)18-34(30)46-38/h5-12,15-18H,13-14,19-22H2,1-4H3,(H,39,43)(H,40,44)(H,41,45)(H,42,46)

InChi Key: KZOLQEUQAFTQFM-UHFFFAOYSA-N