Description
NSMCE3 Polyclonal Antibody | E-AB-16215 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: HCA4, hepatocellular carcinoma-associated protein 4, hepatocellular carcinoma-associated protein HCA4, MAGE-G1 antigen, MAGEG1, MAGEL3, melanoma antigen, family G, 1, melanoma-associated antigen G1, necdin-like 2, necdin-like gene 2, necdin-like protein 2, NSE3, NSMCE3
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Immunology
Background: The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).
Concentration: 1.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human NDNL2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 34 kDa
Molecular Weight(Observed): N/A