NSP1 (SARS-CoV-2) Polyclonal Antibody | AB0385

Goat Anti-SARS-CoV-2 NSP1 (SARS-CoV-2) IgG Polyclonal AntibodyAB0385

Overview: Host translation inhibitor Nsp1 is part of the multifunctional protein replicase polyprotein 1ab that is involved in the transcription and replication of viral RNA. NSP1 inhibits the host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Therefore, Nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response by suppressing host gene expression.

Other Names: Host translation inhibitor, Nsp1 SARS Coronavirus-2 antibody.

Other Names: Host translation inhibitor, Nsp1 SARS Coronavirus-2 antibody.

Concentration: 3 mg/ml

Antibody Type: Primary

Target Type: anti-NSP1 (SARS-CoV-2)

Accession Number: N/A

Host Species: Goat

Immunogen Species: SARS-CoV-2

Immunogen Type: Recombinant protein

Immunogen: Affinity purified recombinant fusion protein Nsp1 of SARS-CoV-2 produced in E. coli.

Isotype: IgG

Clonality: Polyclonal

Confirmed Reactive Species: Reacts with SARS-CoV-2 protein

Specificity Detail: In lysates of transfected cells with the plasmid containing the sequence used, detects the fusion protein by Western blot.

Buffer: PBS, 20% glycerol and 0.05% sodium azide

Purification: Epitope affinity purified

Conjugation: Unconjugated

Format: N/A

Application: WB

Concentration/Dilution: WB:1:500-1:2,000

Storage:

References: N/A