NTRK3 Antibody (Center) [APR04760G]

NTRK3 Antibody (Center) [APR04760G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This NTRK3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 393-426 amino acids from the Central region of human NTRK3.

Cellular Localisation: Membrane; Single-pass type I membrane protein.

Molecular Weight: 94428

Clone: Polyclonal

Gene Name: NTRK3

Gene ID: 4916

Function: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.

Summary: Tissue Location: Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, FC

Dilution: FC--1:25 WB--1:1000

Synonyms: NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, NTRK3, TRKC