NUCKS1 Antibody (N-term) [APR06176G]

NUCKS1 Antibody (N-term) [APR06176G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This NUCKS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human NUCKS1.

Cellular Localisation: Nucleus. Chromosome

Molecular Weight: 27296

Clone: Polyclonal

Gene Name: NUCKS1 {ECO:0000303|PubMed:26323318, ECO:0000312|HGNC:HGNC:29923}

Gene ID: 64710

Function: Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR) (PubMed:26323318) . Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D- loop structures, but with less affinity than RAD51AP1 (PubMed:26323318) .

Summary: Tissue Location: Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1, P1, NUCKS1, NUCKS