Nucleostemin (GNL3) Antibody (C-term) [AMM06861G]

Nucleostemin (GNL3) Antibody (C-term) [AMM06861G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This Nucleostemin (GNL3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 amino acids from the C-terminal region of human Nucleostemin (GNL3) .

Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:Q811S9}. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}

Molecular Weight: 61993

Clone: Polyclonal

Gene Name: GNL3

Gene ID: 26354

Function: May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity) .

Summary: Tissue Location: Increased levels in lung tissue in cancer patients.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, Novel nucleolar protein 47, NNP47, Nucleolar GTP-binding protein 3, Nucleostemin, GNL3, E2IG3, NS