OAC1 | B1079

OAC1 is an Oct4-activating compound that activates expression through the Oct4 gene promoter. In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC1 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts. OAC1 also upregulates mRNA expression of Oct-4, Sox-2 and Nanog, as well as Tet1.

OAC1 is an Oct4-activating compound that activates expression through the Oct4 gene promoter. In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC1 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts. OAC1 also upregulates mRNA expression of Oct-4, Sox-2 and Nanog, as well as Tet1.

B1079 | OAC1 DataSheet

Alternate Name/Synonyms: N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide

Appearance: Beige solid

Formulation: N/A

CAS Number: 300586-90-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₁N₃O

Molecular Weight: 237.26

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml) or EtOH (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An Oct-4 activator

MDL Number: N/A

PubChem CID: 789882

SMILES: C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3

InChi: InChI=1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)

InChi Key: HWJRIFZDXJKJJN-UHFFFAOYSA-N