OAS2 Polyclonal Antibody | BS65788

OAS2 Polyclonal Antibody | BS65788 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Dog,Pig,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As) . These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: OAS2 Polyclonal Antibody detects endogenous levels of OAS2 protein.

Molecular Weight: 82kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: (2-5'') oligo (A) synthase 2; (2-5') oligo (A) synthetase 2; 2''-5''-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; 2-5A synthase 2; 2-5A synthetase 2; MGC78578; OAS2; OAS2_HUMAN; p69 OAS / p71 OAS; p69OAS / p71OAS. 聽

Immunogen: KLH conjugated synthetic peptide derived from human OAS2:401-500/719

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: