OAT Antibody | 22-072

OAT Antibody | 22-072 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-439 of human OAT (NP_000265.1) .

Research Area: Neuroscience, Signal Transduction

Tested Application: WB, IP

Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: SW480

Positive Control 2: MCF7

Positive Control 3: 293T

Positive Control 4: A-549

Positive Control 5: HepG2

Positive Control 6: Mouse liver

Molecular Weight: Observed: 47kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: OAT, DKFZp781A11155, HOGA, OKT, GACR, OATASE

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.