Description
OAT Antibody | 22-072 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-439 of human OAT (NP_000265.1) .
Research Area: Neuroscience, Signal Transduction
Tested Application: WB, IP
Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: SW480
Positive Control 2: MCF7
Positive Control 3: 293T
Positive Control 4: A-549
Positive Control 5: HepG2
Positive Control 6: Mouse liver
Molecular Weight: Observed: 47kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: OAT, DKFZp781A11155, HOGA, OKT, GACR, OATASE
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.