OATD-01 | B3334

OATD-01 is a small molecule inhibitor of acidic mammalian chitinase (AMCase) (IC50 = 9 nM) and chitotriosidase (CHIT1) (IC50 = 26 nM). OATD-01 displays robust anti-fibrotic activity in multiple animal models

OATD-01 is a small molecule inhibitor of acidic mammalian chitinase (AMCase) (IC50 = 9 nM) and chitotriosidase (CHIT1) (IC50 = 26 nM). OATD-01 displays robust anti-fibrotic activity in multiple animal models

B3334 | OATD-01 DataSheet

Alternate Name/Synonyms: 5-[4-[(2S,5S)-5-[(4-Chlorophenyl)methyl]-2-methyl-4-morpholinyl]-1-piperidinyl]-1H-1,2,4-triazol-3-amine OATD01

Appearance: Solid

Formulation:

CAS Number: 2088453-21-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₇ClN₆O

Molecular Weight: 390.92

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and selective chitinase inhibitor

MDL Number:

PubChem CID: 126642132

SMILES: C[C@H]1CN(C2CCN(C3=NN=C(N)N3)CC2)[C@@H](CC4=CC=C(Cl)C=C4)CO1

InChi: InChI=1S/C19H27ClN6O/c1-13-11-26(17(12-27-13)10-14-2-4-15(20)5-3-14)16-6-8-25(9-7-16)19-22-18(21)23-24-19/h2-5,13,16-17H,6-12H2,1H3,(H3,21,22,23,24)/t13-,17-/m0/s1

InChi Key: STWVLEKJQQRGMO-GUYCJALGSA-N