OPG Antibody| F43211-0.4ML

OPG Antibody| F43211-0.4ML | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IF, IHC, ELISA

Application Details: Western blot: 1:1000, Immunofluorescence: 1:10-1:50, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the OPG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This OPG antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 243-271 from the human protein was used as the immunogen for this OPG antibody.

Storage: Aliquot the OPG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A