OR4M1 Antibody (C-term) [APR14205G]

OR4M1 Antibody (C-term) [APR14205G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This OR4M1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human OR4M1.

Cellular Localisation: Cell membrane; Multi-pass membrane protein {ECO:0000255|RuleBase:RU363047}

Molecular Weight: 35488

Clone: Polyclonal

Gene Name: OR4M1 {ECO:0000303|PubMed:31230984, ECO:0000312|HGNC:HGNC:14735}

Gene ID: 441670

Function: Olfactory receptor that acts as a receptor of Asprosin hormone at the surface of hepatocytes to promote hepatocyte glucose release (PubMed:31230984) . Also binds Asprosin in the arcuate nucleus of the hypothalamus, thereby stimulating appetite by promoting orexigenic AgRP neuronal activity (By similarity) . In testis, Asprosin- binding promotes sperm progressive motility and enhances male fertility (By similarity) . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase, resulting in an elevation of intracellular cAMP (By similarity) .

Summary: Tissue Location: Highly expressed in the testis and olfactory bulb.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Olfactory receptor 4M1, Olfactory receptor OR14-7, OR4M1