ORC6 Antibody | 23-316

ORC6 Antibody | 23-316 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human ORC6 (NP_055136.1) .

Research Area: Other

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: Jurkat

Positive Control 2: SW620

Positive Control 3: PC-3

Positive Control 4: HeLa

Positive Control 5: Mouse liver

Positive Control 6: Mouse brain

Molecular Weight: Observed: 28kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: ORC6L, origin recognition complex, subunit 6 homolog-like (yeast) , ORC6, origin recognition complex subunit 6, subunit 6-like (yeast) , subunit 6 (yeast homolog) -like, ORC6L

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.