OSBPL10 Antibody (C-term) [APR08886G]

OSBPL10 Antibody (C-term) [APR08886G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This OSBPL10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 669-695 amino acids from the C-terminal region of human OSBPL10.

Cellular Localisation: Cytoplasm, cytoskeleton Note=Associates with microtubules.

Molecular Weight: 83970

Clone: Polyclonal

Gene Name: OSBPL10

Gene ID: 114884

Function: Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable) . Plays a role in negative regulation of lipid biosynthesis (PubMed:19554302) . Negatively regulates APOB secretion from hepatocytes (PubMed:19554302, PubMed:22906437) . Binds cholesterol and acidic phospholipids (PubMed:22906437) . Also binds 25- hydroxycholesterol (PubMed:17428193) . Binds phosphatidylserine (PubMed:23934110) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Oxysterol-binding protein-related protein 10, ORP-10, OSBP-related protein 10, OSBPL10, ORP10, OSBP9