OSMI-1 | B1916

OSMI-1 is a potent, cell-permeable, O-GlcNAc transferase (OGT) inhibitor. inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.

OSMI-1 is a potent, cell-permeable, O-GlcNAc transferase (OGT) inhibitor. inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.

B1916 | OSMI-1 DataSheet

Alternate Name/Synonyms: αR-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-benzeneacetamide, OSMI 1

Appearance: White solid

Formulation: N/A

CAS Number: 1681056-61-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₂₅N₃O₆S₂

Molecular Weight: 563.64

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, cell-permeable, O-GlcNAc transferase (OGT) inhibitor.

MDL Number: N/A

PubChem CID: 118634407

SMILES: COC1=CC=CC=C1C(C(=O)N(CC2=CC=CO2)CC3=CC=CS3)NS(=O)(=O)C4=CC5=C(C=C4)NC(=O)C=C5

InChi: InChI=1S/C28H25N3O6S2/c1-36-25-9-3-2-8-23(25)27(28(33)31(17-20-6-4-14-37-20)18-21-7-5-15-38-21

InChi Key: IYIGLWQQAMROOF-HHHXNRCGSA-N