Oxamflatin | 2250

A potent inhibitor of mammalian histone deacetylases (HDACs) (IC₅₀ = 15.7 nM). A novel antitumor agent; oxamflatin modifies epigenetic status and gene expression, increases blastocyst quality, and subsequently enhances the nuclear reprogramming and developmental potential of SCNT (somatic cell nuclear transfer) embryos.

Oxamflatin is a potent inhibitor of mammalian histone deacetylases (HDACs) (IC₅₀ = 15.7 nM) and an antitumor agent.

2250 | Oxamflatin DataSheet

Alternate Name/Synonyms: N-​hydroxy-​5-​[3-​[(phenylsulfonyl)amino]phenyl]-​2E-​penten-​4-​ynamide; Metacept 3

Appearance: White to Off-white Solid

Formulation: N/A

CAS Number: 151720-43-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₄N₂O₄S

Molecular Weight: 342.37

Cell-Permeable?: Yes

Purity: ≥95%

Solubilities: DMSO (5 mg/ml) or EtOH (0.5 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A potent inhibitor of mammalian histone deacetylases (HDACs)

MDL Number: MFCD00949087

PubChem CID: 5353852

SMILES: C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)C#CC=CC(=O)NO

InChi: InChI=1S/C17H14N2O4S/c20-17(18-21)12-5-4-7-14-8-6-9-15(13-14)19-24(22,23)16-10-2-1-3-11-16/h1-3,5-6,8-13,19,21H,(H,18,20)/b12-5+

InChi Key: QRPSQQUYPMFERG-LFYBBSHMSA-N