Description
Ozanimod (RPC1063) is an orally bioavailable agonist of the sphingosine-1-phosphate receptor subtypes 1 (S1P1) and 5 (S1P5). S1P receptors belong to the family of G-protein-coupled receptor which contains five subtypes, denoting S1P1-5. S1P receptors are involved in coronary artery caliber, endothelial integrity, cardiac function, and lymphocyte recirculation.
Ozanimod (RPC1063) is an orally bioavailable agonist of the sphingosine-1-phosphate receptor subtypes 1 (S1P1) and 5 (S1P5). S1P receptors belong to the family of G-protein-coupled receptor which contains five subtypes, denoting S1P1-5. S1P receptors are involved in coronary artery caliber, endothelial integrity, cardiac function, and lymphocyte recirculation.
Alternate Name/Synonyms: (S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H- inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile; RPC1063
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1306760-87-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₂₄N₄O₃
Molecular Weight: 404.46
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: Apotent agonist of the sphingosine-1-phosphate receptor subtypes 1 (S1P1) and 5 (S1P5).
MDL Number: N/A
PubChem CID: 52938427
SMILES: CC(C)OC1=C(C=C(C=C1)C2=NC(=NO2)C3=C4CCC(C4=CC=C3)NCCO)C#N
InChi: InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3-4-18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1-2H3/t20-/m0/s1
InChi Key: XRVDGNKRPOAQTN-FQEVSTJZSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |