p100 Antibody (TPX2)| F40192-0.4ML

p100 Antibody (TPX2)| F40192-0.4ML | Gentaur UK, US & Europe Distribution

Background: p100 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. [UniProt]

Format: Purified

Clone: 19AT738.292

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1

Species Reactivity: Human, Mouse

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:100-1:500

Application Note: Titration of the p100 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This p100 antibody is available for research use only.

Purity: Purified

Immunogen: A KLH conjugated synthetic peptide from the human protein was used as immunogen for this p100 antibody.

Storage: Aliquot the p100 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A