P4HA2 Antibody | 19-321

P4HA2 Antibody | 19-321 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 234-533 of human P4HA2 (NP_001136070.1) .

Research Area: Cancer, Cell Cycle, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: SKOV3

Positive Control 2: Mouse brain

Positive Control 3: Rat brain

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 65kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: MYP25, prolyl 4-hydroxylase subunit alpha-2, 4-PH alpha 2, C-P4Halpha (II) , collagen prolyl 4-hydroxylase alpha (II) , procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase) , alpha polypeptide II, procollagen-proline, 2-oxoglutarate-4-dioxygenase subunit alpha-2, prolyl 4-hydroxylase, alpha polypeptide II

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.