Description
P4HTM Antibody | 22-028 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 294-563 of human P4HTM (NP_808807.2) .
Research Area: Cancer
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: MCF7
Positive Control 2: Jurkat
Positive Control 3: 293T
Positive Control 4: U-87MG
Positive Control 5: HeLa
Positive Control 6: Mouse heart
Molecular Weight: Observed: 55kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4, transmembrane prolyl 4-hydroxylase, HIF-PH4, HIF-prolyl hydroxylase 4, HPH-4, P4H with transmembrane domain, Prolyl hydroxlase domain-containing 4, hypoxia-inducible factor prolyl 4-hydroxylase, hypoxia-inducible factor prolyl hydroxylase 4, proline 4-hydroxylase, prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.