Additional Information
Size:  | 
                                                    100 µl  | 
                                                
Target:  | 
                                                    p53 (pSer315)  | 
                                                
Conjugate:  | 
                                                    ATTO 633  | 
                                                
Research Area:  | 
                                                    Cancer | Cell Cycle | p53 Pathway | Cancer | Tumor suppressors | Apoptosis | Cell Signaling | Epigenetics and Nuclear Signaling | DNA/RNA | DNA Damage and Repair  | 
                                                
Alternative Name:  | 
                                                    p53 tumor suppressor Antibody, Cellular tumor antigen p53 Antibody, Antigen NY-CO-13 Antibody, Phosphoprotein p53 Antibody, Tumor protein 53 Antibody, BCC7 Antibody, p53 Antibody, TP53 Antibody, P53_HUMAN Antibody, FLJ92943 Antibody, Mutant tumor pro  | 
                                                
Category:  | 
                                                    Antibodies  | 
                                                
Product Type:  | 
                                                    Polyclonal Antibody  | 
                                                
Immunogen:  | 
                                                    Synthetic phospho-peptide from human p53 around the phosphorylation site of serine 315 (pSer315).  | 
                                                
Immunogen Species:  | 
                                                    Human  | 
                                                
Applications:  | 
                                                    WB, IHC, IP, ELISA  | 
                                                
Host:  | 
                                                    Rabbit  | 
                                                
Isotype:  | 
                                                    N/A  | 
                                                
Species Reactivity:  | 
                                                    Human  | 
                                                
Antibody Dilution:  | 
                                                    WB (1:250-1:1000); IHC (1:50-1:150); IP (1-2.5 ug per mg lysate); ELISA (1:5000); optimal dilutions for assays should be determined by the user.  | 
                                                
Purification:  | 
                                                    Peptide Affinity Purified  | 
                                                
Storage Buffer:  | 
                                                    PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide  | 
                                                
Concentration:  | 
                                                    N/A  | 
                                                
Specificity:  | 
                                                    Detects endogenous levels of p53 protein only when phosphorylated at serine 315 (pSer315). Detects a band at ~43 kDa.  | 
                                                
Storage:  | 
                                                    -20ºC  | 
                                                
Shipping:  | 
                                                    Blue Ice or 4ºC  | 
                                                
Certificate of Analysis:  | 
                                                    N/A  | 
                                                
Cellular Localization:  | 
                                                    Mitochondrion Matrix, Endoplasmic Reticulum, Nucleus Pml Body, Nucleus, Pml Body, Cytoplasm, Cytosol, Mitochondrion, Nuclear Chromatin, Nuclear Matrix, Nucleolus, Nucleoplasm, Intracellular, Protein Complex, Replication Fork  | 
                                                
Tissue Specificity:  | 
                                                    Ubiquitous. Isoforms are expressed in a wide range of normal tissues but in a tissue-dependent manner. Isoform 2 is expressed in most normal tissues but is not detected in brain, lung, prostate, muscle, fetal brain, spinal cord and fetal liver. Isofo  | 
                                                
Accession Number:  | 
                                                    NP_000537.3  | 
                                                
Gene ID:  | 
                                                    7157  | 
                                                
Swiss-Prot:  | 
                                                    P04637  | 
                                                
Field of Use:  | 
                                                    For in vitro research use only.  |