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p70 S6Kβ polyclonal Antibody | BS91009
- SKU:
- BW-BS91009
- Availability:
- Usually ships in 5 working days
Description
p70 S6Kβ polyclonal Antibody | BS91009 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, mouse, rat
Application: WB ICC IHC FC
Application Range: WB:1:500 ICC:1:200 IHC:1:200 FC:1:100-1:200
Background: p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. p70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5' oligopyrimidine tract mRNAs. A second isoform, p85 S6 kinase, is derived from the same gene and is identical to p70 S6 kinase except for 23 extra residues at the amino terminus, which encode a nuclear localizing signal. Both isoforms lie on a mitogen activated signaling pathway downstream of phosphoinositide-3 kinase (PI-3K) and the target of rapamycin, FRAP/mTOR, a pathway distinct from the Ras/MAP kinase cascade. Ribosomal protein S6 kinase beta-2 is an enzyme that in humans is encoded by the RPS6KB2 gene. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: p70 S6Kβ polyclonal Antibody detects endogenous levels of p70 S6Kβ protein.
Molecular Weight: 70 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: S6K-beta-2, S6K2, P70S6K2, p70-S6K 2, SRK, S6K-beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70-beta, 70 kDa ribosomal protein S6 kinase 2, EC 2.7.11.1, KS6B2, p70 beta, p70 ribosomal S6 kinase beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70 S6Kbeta, p70 (S6K) beta, p70-beta, p70-S6K 2, P70S6K2, p70S6Kb, Ribosomal protein S6 kinase 70kDa, polypeptide 2, Ribosomal protein S6 kinase beta 2, Ribosomal protein S6 kinase beta-2, Rps6kb2, S6 kinase related kinase, S6 kinase-related kinase, S6K beta 2, S6K beta, S6K-beta, S6K-beta-2, S6K2, Serine/threonine protein kinase 14 beta, Serine/threonine-protein kinase 14B, SRK, STK14B,
Immunogen: peptide
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Peptide affinity purified
Pathway: