PAFR/PAF Receptor Polyclonal Antibody | BS65779

PAFR/PAF Receptor Polyclonal Antibody | BS65779 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,

Application: WB,IHC-P,

Application Range: WB=1:500-2000，IHC-P=1:100-500

Background: The PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PAFR/PAF Receptor Polyclonal Antibody detects endogenous levels of PAFR/PAF Receptor protein.

Molecular Weight: 38kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Platelet-activating factor receptor; PAF receptor; Ptafr; OTTHUMP00000004041; OTTMUSP00000010350; PAF R; PAF-R; PAFR; Platelet activating factor receptor; Platelet-activating factor receptor; PTAFR; PTAFR_HUMAN; RP23-470B20.1.聽聽

Immunogen: KLH conjugated synthetic peptide derived from human PAFR:231-342/342

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: