PAICS Polyclonal Antibody | E-AB-11470

PAICS Polyclonal Antibody | E-AB-11470 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ADE2, ADE2H1, AIR carboxylase, AIRC, DKFZp781N1372, MGC1343, MGC5024, Multifunctional protein ADE2, Multifunctional protein ADE2H1, Paics, PAIS, Phosphoribosylaminoimidazole carboxylase, Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, PUR6, SAICAR synthetase

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Background: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human PAICS

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 47 kDa

Molecular Weight(Observed): N/A