Description
PAICS Polyclonal Antibody | E-AB-11470 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: ADE2, ADE2H1, AIR carboxylase, AIRC, DKFZp781N1372, MGC1343, MGC5024, Multifunctional protein ADE2, Multifunctional protein ADE2H1, Paics, PAIS, Phosphoribosylaminoimidazole carboxylase, Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, PUR6, SAICAR synthetase
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Background: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Concentration: 0.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human PAICS
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 47 kDa
Molecular Weight(Observed): N/A