PAQR8 Antibody (C-term) [APR12720G]

PAQR8 Antibody (C-term) [APR12720G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This PAQR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-354 amino acids from the C-terminal region of human PAQR8.

Cellular Localisation: Cell membrane; Multi-pass membrane protein. Note=Colocalizes with a lysosomal protein CTSD/cathepsin D.

Molecular Weight: 40464

Clone: Polyclonal

Gene Name: PAQR8 (HGNC:15708)

Gene ID: 85315

Function: Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432) . Seems to act through a G (i) mediated pathway (PubMed:23763432) . May be involved in oocyte maturation (By similarity) . Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870) .

Summary: Tissue Location: Highly expressed in the hypothalamus (PubMed:23161870) . Also expressed in spinal cord, kidney and testis

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Membrane progestin receptor beta, mPR beta, Lysosomal membrane protein in brain 1, Progestin and adipoQ receptor family member 8, Progestin and adipoQ receptor family member VIII, PAQR8, C6orf33, LMPB1, MPRB