Description
PARD6A polyclonal Antibody | BS7481 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Rat
Application: WB
Application Range: WB 1:500 - 1:2000
Background: This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PARD6A polyclonal Antibody detects endogenous levels of PARD6A protein.
Molecular Weight: ~ 37 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PARD6A;PAR-6A;PAR6;PAR6C;PAR6alpha;TAX40;TIP-40
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 256-345 of human PARD6A (NP_001032358.1) .
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: